Description
Product Characteristics: KHDRBS2 (KH RNA Binding Domain Containing, Signal Transduction Associated 2) is a Protein Coding gene. Diseases associated with KHDRBS2 include Atrial Septal Defect 2. Among its related pathways are Signaling by GPCR and Signaling by PTK6. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and protein heterodimerization activity. An important paralog of this gene is KHDRBS3.
Target Information: The protein encoded by this gene is similar to the src associated in mitosis, 68 kDa protein, which is an RNA-binding protein and a substrate for Src-family tyrosine kinases during mitosis. This protein has a KH RNA-binding motif and proline-rich motifs which may be SH2 and SH3 domain binding sites. A similar rat protein is an RNA-binding protein which is tyrosine phosphorylated by Src during mitosis. These studies also suggest that the rat protein may function as an adaptor protein for Src by binding the SH2 and SH3 domains of various other proteins. [provided by RefSeq, Jul 2008]